--- gcc/caller-save.c.jj	2010-08-11 21:08:06.000000000 +0200
+++ gcc/caller-save.c	2010-08-11 22:23:12.000000000 +0200
@@ -868,7 +868,10 @@ save_call_clobbered_regs (void)
 	     remain saved.  If the last insn in the block is a JUMP_INSN, put
 	     the restore before the insn, otherwise, put it after the insn.  */
 
-	  if (DEBUG_INSN_P (insn) && last && last->block == chain->block)
+	  if (n_regs_saved
+	      && DEBUG_INSN_P (insn)
+	      && last
+	      && last->block == chain->block)
 	    {
 	      rtx ins, prev;
 	      basic_block bb = BLOCK_FOR_INSN (insn);
--- gcc/testsuite/gcc.dg/pr45259.c.jj	2010-08-11 22:12:19.000000000 +0200
+++ gcc/testsuite/gcc.dg/pr45259.c	2010-08-11 21:43:24.000000000 +0200
@@ -0,0 +1,42 @@
+/* PR debug/45259 */
+/* { dg-do compile } */
+/* { dg-options "-g -O2 -fpic -w" { target fpic } } */
+
+struct S { void (*bar) (long); };
+struct T { struct S *t; };
+int w;
+extern int baz (int);
+
+void
+foo (int x, int u, char *z)
+{
+  struct T *v;
+  static void *y[256] = { &&l1, &&l2 };
+  for (;;)
+    switch (x)
+      {
+      l2:
+	x = 9;
+      case 9:
+	goto *y[*z++];
+      case 10:
+      case 27:
+      case 54:
+      case 99:
+      case 100:
+      case 120:
+      case 122:
+      case 131:
+      case 132:
+      case 134:
+      case 141:
+      case 142:
+	v->t->bar (u);
+	v->t->bar (u);
+      case 143:
+	continue;
+      l1:
+      default:
+	baz (w);
+      }
+}