diff --git a/docs/development/contributing.rst b/docs/development/contributing.rst
index 5089bba8..f713f872 100644
--- a/docs/development/contributing.rst
+++ b/docs/development/contributing.rst
@@ -31,29 +31,15 @@ Testing
 -------
 
 Patchwork includes a `tox`_ script to automate testing. This requires a
-functional database and some Python requirements like *tox*. Refer to
-:doc:`installation` for information on how to configure these.
-
-You may also need to install *tox*. If so, do this now:
+functional database and some Python requirements like *tox*. These can be
+installed using :command:`pip`:
 
 .. code-block:: shell
 
-   $ pip install --user tox
-
-.. tip::
-
-   If you're using Docker, you may not need to install *tox*
-   locally. Instead, it will already be installed inside the
-   container. For Docker, you can run *tox* like so:
-
-   .. code-block:: shell
-
-      $ docker-compose run --rm web tox [ARGS...]
-
-   For more information, refer to :ref:`installation-docker`.
+   $ pip install --user tox tox-docker
 
-Assuming these requirements are met, actually testing Patchwork is quite easy
-to do. To start, you can show the default targets like so:
+Once installed, actually testing Patchwork is quite easy to do. To start, you
+can show the default targets like so:
 
 .. code-block:: shell
 
@@ -66,7 +52,7 @@ parameter:
 
 .. code-block:: shell
 
-   $ tox -e py27-django18
+   $ tox -e py36-django21-mysql
 
 In the case of the unit tests targets, you can also run specific tests by
 passing the fully qualified test name as an additional argument to this
@@ -74,7 +60,7 @@ command:
 
 .. code-block:: shell
 
-   $ tox -e py27-django18 patchwork.tests.SubjectCleanUpTest
+   $ tox -e py36-django21-mysql patchwork.tests.SubjectCleanUpTest
 
 Because Patchwork support multiple versions of Django, it's very important that
 you test against all supported versions. When run without argument, tox will do
diff --git a/docs/development/installation.rst b/docs/development/installation.rst
index 0ab755f4..433c3a41 100644
--- a/docs/development/installation.rst
+++ b/docs/development/installation.rst
@@ -86,12 +86,6 @@ To run unit tests against the system Python packages, run:
 
    $ docker-compose run --rm web python manage.py test
 
-To run unit tests for multiple versions using ``tox``, run:
-
-.. code-block:: shell
-
-   $ docker-compose run --rm web tox
-
 To reset the database before any of these commands, add ``--reset`` to the
 command line after ``web`` and before any other arguments:
 
diff --git a/patchwork/settings/dev.py b/patchwork/settings/dev.py
index 53fa58f6..cfb9256c 100644
--- a/patchwork/settings/dev.py
+++ b/patchwork/settings/dev.py
@@ -19,6 +19,18 @@ try:
 except ImportError:
     debug_toolbar = None
 
+#
+# tox-docker settings
+#
+
+if 'POSTGRES_5432_TCP' in os.environ:
+    os.environ['PW_TEST_DB_HOST'] = os.environ['POSTGRES_HOST']
+    os.environ['PW_TEST_DB_PORT'] = os.environ['POSTGRES_5432_TCP']
+elif 'MYSQL_3306_TCP' in os.environ:
+    os.environ['PW_TEST_DB_HOST'] = os.environ['MYSQL_HOST']
+    os.environ['PW_TEST_DB_PORT'] = os.environ['MYSQL_3306_TCP']
+
+
 #
 # Core settings
 # https://docs.djangoproject.com/en/1.11/ref/settings/#core-settings
diff --git a/tox.ini b/tox.ini
index d4c34e1c..3c71dafd 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,6 +1,7 @@
 [tox]
 minversion = 2.0
-envlist = pep8,docs,py{27,34}-django111,py{35,36}-django{111,20,21,22}
+envlist = pep8,docs,py{27,34}-django111-{mysql,postgres},py{35,36}-django{111,20,21,22}-{mysql,postgres}
+skip_missing_interpreters = True
 skipsdist = True
 
 [testenv]
@@ -17,6 +18,9 @@ deps =
     django22: django>=2.2,<2.3
     django22: djangorestframework>=3.9.2
     django22: django-filter>=2.1,<3.0
+docker =
+    postgres: postgres:9.6
+    mysql: mysql:8.0
 setenv =
     DJANGO_SETTINGS_MODULE = patchwork.settings.dev
     PYTHONDONTWRITEBYTECODE = 1
@@ -24,15 +28,25 @@ setenv =
     py27: PYTHONWARNINGS = once
     py{34,36}:PYTHONWARNINGS = once,ignore::ImportWarning:backports
     py35:PYTHONWARNINGS = once,ignore::ResourceWarning:unittest.suite,ignore::ImportWarning:backports
+    postgres: PW_TEST_DB_TYPE = postgres
+    postgres: PW_TEST_DB_USER = postgres
+    postgres: PW_TEST_DB_PASS = password
+    mysql: PW_TEST_DB_USER = root
+    mysql: PW_TEST_DB_PASS = password
 passenv =
     http_proxy HTTP_PROXY https_proxy HTTPS_PROXY no_proxy NO_PROXY
     PW_TEST_DB_TYPE PW_TEST_DB_USER PW_TEST_DB_PASS PW_TEST_DB_HOST
     PW_TEST_DB_PORT
+dockerenv =
+    postgres: POSTGRES_PASSWORD=password
+    mysql: MYSQL_ROOT_PASSWORD=password
 commands =
-    python {toxinidir}/manage.py test --noinput '{posargs:patchwork}'
+    python {toxinidir}/manage.py test --noinput {posargs:patchwork}
 
 [testenv:bashate]
 deps = bashate
+docker =
+dockerenv =
 whitelist_externals = bash
 commands =
     bash -c "find {toxinidir} \
@@ -43,6 +57,8 @@ commands =
 [testenv:pep8]
 basepython = python2.7
 deps = flake8
+docker =
+dockerenv =
 commands = flake8 {posargs} patchwork patchwork/bin/pwclient
 
 [flake8]
@@ -57,6 +73,8 @@ exclude = ./patchwork/migrations
 [testenv:docs]
 deps =
     -r{toxinidir}/docs/requirements.txt
+docker =
+dockerenv =
 commands =
     sphinx-build -E -W -b dirhtml -d docs/_build/doctrees docs docs/_build/html
 
@@ -67,9 +85,6 @@ deps =
     -r{toxinidir}/requirements-prod.txt
 commands = pylint patchwork --rcfile=pylint.rc
 
-[testenv:venv]
-commands = {posargs}
-
 [testenv:coverage]
 basepython = python2.7
 deps =
